In this post:
- Ketamine Therapy in Columbia
- What Does Ketamine Therapy Cost at Columbia Clinics?
- Does Insurance Cover Ketamine Therapy in Columbia?
- Ketamine-Assisted Therapy (KAP) Costs in Columbia
- How to Make Ketamine Therapy More Affordable
- Q&A
Columbia ketamine clinic pricing ranges from $300 to $1,300 per session for patients who pay full price. However, ketamine therapy costs in Columbia vary based on the treatment type and facility, which can influence insurance coverage, financing options, and potential discounts, possibly reducing the total payment by 80% or more.
This article details the costs of IV ketamine therapy and Spravato® in Columbia, Maryland. It explains the pricing out of pocket and with insurance, the differences between in-network and out-of-network insurance coverage, and other cost-saving strategies for affordable ketamine therapy in Columbia.
Disclaimer: The pricing figures in this article reflect typical industry ranges reported by ketamine clinics and patients in the Columbia, Maryland area. These are not specific to Avesta Ketamine and Wellness. Actual costs may vary based on provider, insurance coverage, treatment protocol, and individual clinical needs.
Ketamine Therapy in Columbia

Paying for ketamine is often a significant hurdle for those who can benefit from this life-changing therapy. The primary factor affecting ketamine therapy costs in Columbia, MD, is the treatment type.
Two of the most common and effective ketamine treatment methods are IV infusions and Spravato®, a nasal spray form of ketamine analog, esketamine. Patients sometimes combine these treatments with ketamine-assisted therapy (KAP) for an added cost.
Ketamine infusions
Ketamine infusion therapy administered via IV into the veins is the most common method nationwide, including in Columbia. IV ketamine therapy has decades of evidence proving its ability to rapidly elevate mood and improve symptoms of severe depression, anxiety, PTSD, and chronic pain.
Spravato® (esketamine)
Spravato®, administered as a nasal spray, offers another clinical ketamine treatment option. It is FDA-approved for people with treatment-resistant major depressive disorder and can be more appealing to those opposed to IV needles.
What Does Ketamine Therapy Cost at Columbia Clinics?

Both ketamine therapies can be expensive out-of-pocket for Columbia residents. Average industry prices range from $2,400 to over $15,000 for a complete series of IV ketamine or Spravato treatments because both involve multiple sessions under the supervision of trained clinicians.
Additionally, most Maryland insurers do not cover IV ketamine therapy because the protocol is not FDA-approved for mental health. Spravato®, which is the only FDA-approved ketamine treatment option, only provides coverage for qualifying conditions. As a result, some patients will find themselves paying for ketamine therapy in Columbia out of pocket.
Average Out-of-Pocket Costs for IV Ketamine in Columbia
Patients without insurance coverage typically pay per ketamine infusion, with a complete treatment series requiring 6–8+ sessions over 2–3 weeks. Booster sessions may also be needed for ongoing relief.
Estimated Range per Infusion: $400 – $1,000
Estimated Cost for Full Series: $2,400 – $8,000
Average Out-of-Pocket Costs for Spravato® in Columbia
Spravato® treatment involves an 8-week protocol with costs for both the medication and required in-clinic monitoring.
Estimated Cost per Session: $600–$900 (dose) + $200–$400 (monitoring)
Estimated Cost for Full Protocol: $10,800 – $15,600
Does Insurance Cover Ketamine Therapy in Columbia?

Patients in Columbia, Maryland, can access insurance coverage for ketamine therapy depending on their treatment type and plan.
Most insurers cover Spravato® for conditions like treatment-resistant depression or major depressive disorder. Coverage requires a documented diagnosis, a physician’s recommendation, and concurrent use of an oral antidepressant. Insurance lowers the cost significantly for eligible patients.
IV ketamine is less commonly covered. However, some Columbia clinics, including Avesta, work with major insurers to help reduce costs where possible. Some cost-offsetting options include partial coverage for non-ketamine-related services (i.e., blood tests and clinical supervision) and superbill reimbursement support. Insurance benefits, where applicable, also depend on whether the clinic is in-network or out-of-network with the patient’s provider.
In-network vs. Out of Network
In-network ketamine clinics work directly with insurance providers to offer care at pre-negotiated rates. This usually results in lower out-of-pocket costs for patients. Patients may pay only a small co-pay per visit, depending on the plan.
Estimated IV Ketamine Costs (In-Network)
- Per session: $0 – $75*
- Complete treatment series (6–8 sessions): $0 – $600
Estimated Spravato® Costs (In-Network)
- Per session co-pay: $30 – $50
- Medication: As low as $10 per dose
- Total 8-week protocol: $480 – $720
Out-of-network ketamine clinics do not have contracted rates with insurance companies, meaning coverage may be limited. However, these insurance plans may reimburse parts of the treatment, such as observation, monitoring, and screening fees.
Typical IV Ketamine Costs (Out-of-Network)
- Per session: $20 – $250 per visit*
- Total cost: $120 – $1,600
Typical Spravato® Costs (Out-of-Network)
- Per session: $250 – $600 per visit*
- Total protocol: $3,000 – $7,200
* These price estimates are based on Avesta’s experience with major commercial providers. The actual cost per session is highly specific to the ketamine clinic, insurance plan, deductible, and co-insurance benefits.
Ketamine-Assisted Therapy (KAP) Costs in Columbia

In addition to standalone ketamine treatments, some patients in Columbia combine their infusions or Spravato® sessions with psychotherapy, a service known as ketamine-assisted psychotherapy (KAP). This approach integrates talk therapy before, during, or after treatment to help patients process insights, explore emotional breakthroughs, and extend the benefits of their ketamine experience.
KAP therapist fees add to the total ketamine protocol cost in Columbia. However, some insurance plans do cover traditional talk therapy in certain situations, even if they won’t pay for the ketamine itself.
Average Maryland therapist: $160 per hour

How to Make Ketamine Therapy More Affordable
Affordable ketamine therapy in Columbia is possible for patients with and without insurance coverage. Residents have several options to offset costs when paying for ketamine, including financing, reimbursement, and discounts.
Financing
Many Maryland ketamine clinics offer financing through healthcare credit card companies, an invaluable resource for managing upfront costs. Avesta partners with two of the most popular, Advance Care and CareCredit.
- Advance Care healthcare credit options feature flexible plans with manageable monthly payments and interest-free financing.
- CareCredit provides a range of short-term plans featuring low-interest and interest-free options. Patients can apply for a credit line dedicated to ketamine expenses, allowing them to manage the costs through fixed monthly payments.
Reimbursement
Services like Reimbursify help patients maximize insurance reimbursements for ancillary ketamine therapy services, including consultations and monitoring. Call Avesta’s insurance team to learn more.
Discounts
Specific patient groups, such as veterans and first responders, might qualify for discounted rates at some Columbia clinics. Participating in clinical trials is another way to access ketamine therapy at reduced or no cost. Patients can find ongoing ketamine trials in Maryland through resources like ClinicalTrials.gov.
Employer benefits
Columbia residents should look into employer healthcare plans. Increasingly, companies partnering with benefits administrators like Enthea offer coverage for ketamine therapy, similar to dental or vision benefits.
The Bottom Line

Columbia’s ketamine prices are comparable to national averages, ranging from $300 to $1,300 per session, depending on the treatment type and clinic. However, navigating ketamine therapy costs in Columbia, Maryland, involves understanding the various treatment methods, a patient’s specific insurance coverage, and ways to offset out-of-pocket costs.
Patients in Columbia can schedule a free consultation with Avesta’s insurance experts to determine their best ketamine therapy pricing and options.

Q&A
Do insurance providers cover ketamine therapy in Columbia?
Yes—Spravato® is widely covered by major insurers due to FDA approval. Qualifying patients pay about $10–$50 co-pay per session. IV ketamine is less commonly covered, but some insurers cover or reimburse portions of the visit.
Which insurers cover ketamine in Columbia?
Spravato® is typically covered by Aetna, Cigna, United Healthcare, CareFirst (BCBS), Medicare, and Tricare. Avesta is in-network with Cigna and is a VA-approved provider for qualifying veterans in the DC, Maryland, and Virginia areas.
Can I get reimbursed if my insurance doesn’t cover treatment?
Yes. Patients may receive partial reimbursement for non-ketamine services like medical monitoring or office visits. Avesta provides superbills with the proper billing codes to submit claims directly to insurers.
Are there financing options for ketamine treatment?
Yes. Patients sometimes partner with Advance Care and CareCredit for flexible, interest-free financing. Patients can also use Reimbursify, a free tool that may help recover 20%–80% of out-of-pocket costs through insurance.
How much does ketamine therapy typically cost in Columbia?
Without insurance, IV ketamine runs $400–$1,000 per session. Spravato® costs $600–$900 per session, plus $200–$400 for monitoring. With insurance, co-pays can drop to as low as $0–$75 for IV or $10–$50 for Spravato®.
How do I verify my coverage before starting treatment?
Start by calling your insurance provider and asking whether your plan includes Spravato® or IV ketamine coverage. Avesta staff can also help verify benefits and provide documentation needed for prior authorization.