Written by Deborah Tan. Medically reviewed by Dr. Ladan Eshkevari, CRNA, PhD, FAAN on July 25, 2026.
Ketamine therapy in Maryland costs $300 to $1,300 per clinical session, depending on the treatment type, the clinic, and your insurance. At Avesta’s Bethesda and Columbia clinics, insurance can bring IV ketamine to $0 to $450 per session and Spravato medication to $0. For national pricing across every treatment type, see our complete guide to how much ketamine therapy costs.
How much does ketamine therapy cost in Maryland?
Maryland ketamine therapy costs $300 to $1,300 per session, in line with national averages. The price depends on four things: the treatment type (IV, IM, Spravato, or ketamine-assisted psychotherapy), your insurance, the clinic’s location, and the level of medical supervision. Ketamine is an evidence-based treatment for several conditions[1], including depression, anxiety, PTSD, and chronic pain.
| Treatment type | Typical Maryland range | At Avesta (Bethesda and Columbia) |
|---|---|---|
| IV ketamine (mental health) | $400 – $1,000 per session | $0 – $450 with insurance; $450 self-pay ($425 each in a 6-session package) |
| IV ketamine (chronic pain) | Varies widely | $1,400 cash per session |
| Spravato (esketamine) | $900 – $1,300 per visit uninsured | $0 medication with insurer approval, plus $0 – $250 office visit |
| IM injections | $275 – $400+ per session | $450 ($425 each in a 6-session package) |
| Ketamine-assisted psychotherapy (KAP) | Varies by protocol | Quoted individually; ask our team |
How much do ketamine infusions cost in Maryland?
Ketamine infusions in Maryland typically cost $400 to $1,000 per session, and a standard six-session induction runs $2,400 to $6,000 before insurance. According to the American Society of Ketamine Physicians, Psychotherapists & Practitioners, $400 to $800 per treatment[2] is a reasonable price; clinics charging much more may be asking too much.
Prices climb in urban centers like Baltimore, Bethesda, and Annapolis, where overhead is higher, and at clinics staffed by licensed, experienced providers rather than patient-care technicians. Adding structured psychotherapy (KAP) raises the total further, since Maryland therapists charge about $160 per hour[6] on top of infusion and monitoring fees.
At Avesta’s Maryland clinics, insurance can bring an IV ketamine session to $0 to $450; full details are below.
How much does Spravato cost in Maryland?
With insurer approval, the Spravato medication costs Maryland patients $0, plus a $0 to $250 office visit per session at Avesta. Without insurance, Spravato runs about $900 to $1,300 per visit nationally, combining the medication ($800 for 56mg, $1,200 for 84mg) and in-clinic monitoring fees.
Spravato (esketamine) is FDA-approved: approved in 2019 for treatment-resistant depression and in 2025 as a monotherapy[3]. Because it is FDA-approved, most major plans cover it. Eligible commercially insured patients can also pay as little as $10 per treatment through the SPRAVATO withMe program[4].
Does insurance cover ketamine therapy in Maryland?
IV and IM ketamine are usually not covered in Maryland because they are administered off-label; ketamine is FDA-approved as an anesthetic, not as a mental health treatment. Avesta is an exception: we are in-network for IV ketamine with Cigna, the VA, and Workers’ Compensation. Spravato is FDA-approved and covered by most major plans; Avesta is in-network for Spravato with Cigna, Aetna, the VA, and Maryland Medicaid.
We are working to join the CareFirst (BCBS) network. Until that completes, CareFirst members pay out-of-network rates and receive a superbill for reimbursement. For every payer, pre-authorization steps, and billing codes, see our insurance page.
Is ketamine infusion covered by Medicare for pain management?
No. Medicare does not cover ketamine infusions for pain management, because pain infusions are an off-label use of the drug. Medicare can cover Spravato (esketamine) for treatment-resistant depression[5] when its clinical criteria are met, but that coverage does not extend to IV ketamine for pain.
Avesta is out-of-network with Medicare. Maryland Medicare patients pay our self-pay rates: $450 per mental health session ($425 each in a 6-session package) and $1,400 per chronic pain infusion. HSA/FSA funds and financing (below) can offset these costs.
How much is ketamine therapy at Avesta’s Maryland clinics?
At Avesta’s Bethesda and Columbia clinics, IV ketamine costs $0 to $450 per session with insurance, depending on your plan. A standard induction is 6 sessions over 2 to 3 weeks. Per-session costs by payer:
- Veterans Affairs: in-network, VA pre-authorizes. $0 per session.
- Cigna: in-network. $0 to $220 per session depending on plan.
- Workers’ Compensation: in-network. Can be $0 per session.
- Aetna: out-of-network for IV, we bill on your behalf. $0 to $300 per session.
- United Healthcare: out-of-network, we bill on your behalf. $0 to $450 per session.
- BCBS / CareFirst: out-of-network. $450 per session, $425 each in a 6-session package.
- No insurance (self-pay): $450 per session, $425 each in a 6-session package.
IM ketamine is cash pay: $450 per session, or $425 per session in a 6-session package. Spravato costs have two parts: with insurer approval and an in-network payer (Cigna, Aetna, the VA, Workers’ Comp, or Maryland Medicaid), the medication costs you nothing and the office visit runs $0 to $250 per session. Chronic pain infusions are $1,400 per session, cash.
Your exact cost depends on your plan’s deductible and coinsurance. Our insurance specialist gives you a plan-specific estimate before your first session.
How can Maryland patients pay less for ketamine therapy?
Most Maryland patients lower their cost three ways: pre-tax HSA/FSA dollars, interest-free financing, and discount or benefit programs.
HSA/FSA accounts: ketamine therapy is an eligible expense for Health Savings and Flexible Spending Accounts. Avesta accepts both.
Financing: Avesta partners with Advance Care Card for 6 or 14 months of interest-free financing.
Veterans, service members, and first responders: Avesta is in-network with the VA, and partners with nonprofits like Ten Ten Life that fund trauma-informed ketamine care for eligible applicants. See our Veterans page.
Employer benefits: a growing number of employers cover ketamine therapy through benefits administrators. Avesta’s Maryland clinics partner with Enthea and Tara Mind to offer subsidized care for eligible patients.
FAQs About Ketamine Therapy Cost in Maryland
How much does ketamine therapy cost in Maryland with insurance?
At Avesta’s Bethesda and Columbia clinics, $0 to $450 per session for IV ketamine depending on your plan, and $0 medication plus a $0 to $250 office visit for Spravato with insurer approval.
What is the cheapest ketamine treatment in Maryland?
For insured patients, in-network IV ketamine or Spravato can cost $0 per session. For self-pay patients, IM and IV ketamine at Avesta are $425 to $450 per session in a 6-session package.
Does Maryland Medicaid cover ketamine or Spravato?
Maryland Medicaid covers Spravato, which is FDA-approved, and Avesta is in-network with Maryland Medicaid for it. IV ketamine is off-label and not covered.
Does CareFirst cover ketamine therapy in Maryland?
Most CareFirst plans cover Spravato. Avesta is working to join the CareFirst network; until then CareFirst members pay out-of-network rates ($450 per IV session) and receive a superbill for reimbursement.
Where does Avesta offer ketamine therapy in Maryland?
Bethesda and Columbia. Both clinics offer IV and IM ketamine, Spravato, and ketamine-assisted psychotherapy.
Ready for a plan-specific number? Contact Avesta’s Maryland clinics for a free insurance and pricing consultation, or see the national picture on our ketamine therapy cost guide.
References
- Walsh, Z., Mollaahmetoglu, O. M., Rootman, J., et al. “Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review.” BJPsych Open, 2022. Accessed July 25, 2026.
- American Society of Ketamine Physicians, Psychotherapists & Practitioners. “How to Choose a Ketamine Clinic.” ASKP3. Accessed July 25, 2026.
- Johnson & Johnson. “SPRAVATO® (esketamine) Approved in the U.S. as the First and Only Monotherapy for Adults with Treatment-Resistant Depression.” PR Newswire, January 2025. Accessed July 25, 2026.
- Janssen Pharmaceuticals. “SPRAVATO withMe Savings Program Requirements.” SpravatoHCP. Accessed July 25, 2026.
- Centers for Medicare & Medicaid Services. “Billing and Coding: Esketamine Nasal Spray (Spravato) for Treatment-Resistant Depression.” Medicare Coverage Database. Accessed July 25, 2026.
- TherapyDen. “How Much Do Therapists Charge in the U.S.?” Accessed July 25, 2026.
